Immunocytochemistry (ICC): 1:100 Immunohistochemistry (IHC): 1:100 Western Blotting (WB): 1:1,000
产品信息
Reactive Species
Human, Mouse, Rat
Target UniProt ID
P68133 (Human)
P68139 (Chicken)
Target Alternative Names
Smooth muscle actin
Target Molecular Weight (kDa)
42 kDa
Sensitivity
Endogenous
Host / lsotype
Mouse / IgG2b
Class
Recombinant Antibody
Clone
C4-L
Expression System
CHO
Immunogen
Chicken gizzard actin
Purification
Protein G
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Storage Buffer
PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition
-20°C
背景
Beta-actin (encoded by the ACTB gene) is one of the most abundant and conserved actin isoforms in eukaryotic cells. It plays a fundamental role in maintaining cell structure, facilitating cell motility, and enabling intracellular transport by forming part of the cytoskeleton. Beta-actin is involved in key cellular processes, including cell division, signal transduction, and the formation of actin-based structures like stress fibers and filopodia. Its highly dynamic nature allows for rapid polymerization and depolymerization of actin filaments, which are essential for cellular movement and shape changes. Beta-actin is often used as a housekeeping protein in research due to its stable expression across various cell types.