Anti-Actin, clone C4-L, Recombinant Mouse Monoclonal Ab
克隆号:C4-L
ICC IHC WB
EMS0010
货号 规格 数量. 价格 库存
EMS0010-25μg 25μg
EMS0010-100μg 100μg
EMS0010-500μg 500μg
应用
Immunocytochemistry (ICC): 1:100
Immunohistochemistry (IHC): 1:100
Western Blotting (WB): 1:1,000
产品信息
Reactive Species Human, Mouse, Rat
Target UniProt ID P68133 (Human) P68139 (Chicken)
Target Alternative Names Smooth muscle actin
Target Molecular Weight (kDa) 42 kDa
Sensitivity Endogenous
Host / lsotype Mouse / IgG2b
Class Recombinant Antibody
Clone C4-L
Expression System CHO
Immunogen Chicken gizzard actin
Purification Protein G
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
Beta-actin (encoded by the ACTB gene) is one of the most abundant and conserved actin isoforms in eukaryotic cells. It plays a fundamental role in maintaining cell structure, facilitating cell motility, and enabling intracellular transport by forming part of the cytoskeleton. Beta-actin is involved in key cellular processes, including cell division, signal transduction, and the formation of actin-based structures like stress fibers and filopodia. Its highly dynamic nature allows for rapid polymerization and depolymerization of actin filaments, which are essential for cellular movement and shape changes. Beta-actin is often used as a housekeeping protein in research due to its stable expression across various cell types.
参考文献
Lessard, J.L. (1988) Cell Motil. Cytoskeleton 10: 349-362.