Anti-METTL7A Recombinant Rabbit Monoclonal Ab
克隆号:2P8
ICC IHC WB
ERB0400
货号 规格 数量. 价格 库存
ERB0400-25μg 25μg
ERB0400-100μg 100μg
ERB0400-500μg 500μg
应用
Immunocytochemistry (ICC): 1:1,000
Immunohistochemistry (IHC): 1:1,000
Western Blotting (WB): 1:1,000
产品信息
Reactive Species Human
Target UniProt ID Q9H8H3
Target Alternative Names Thiol S-methyltransferase TMT1A, Methyltransferase-like protein 7A, N6-adenosine-methyltransferase TMT1A, Protein AAM-B, Thiol methyltransferase 1A, TMT1A
Target Molecular Weight (kDa) 30 kDa and 18 kDa
Sensitivity Endogenous
Host / lsotype Rabbit / IgG
Class Recombinant Antibody
Clone 2P8
Expression System CHO
Immunogen Synthetic peptide corresponding to the C-terminal region of human METTL7A.
Purification Protein A
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
METTL7A (Methyltransferase-like 7A) is a methyltransferase enzyme that is involved in the methylation of RNA. As part of the RNA methyltransferase family, METTL7A specifically adds methyl groups to the RNA molecule, a modification that can influence various aspects of RNA metabolism, including stability, splicing, translation, and decay. While much is still being studied about the specific targets and mechanisms of METTL7A, its activity is believed to play a role in regulating gene expression and cellular processes such as cell differentiation and growth. Dysregulation of RNA methylation has been implicated in various diseases, including cancer and neurological disorders, making METTL7A an important focus of ongoing research.
参考文献
Wang, B. et al. (2024) Sci Rep. 14(1):3476.