Immunocytochemistry (ICC): 1:1,000 Immunohistochemistry (IHC): 1:1,000 Western Blotting (WB): 1:1,000
产品信息
Reactive Species
Human
Target UniProt ID
Q9H8H3
Target Alternative Names
Thiol S-methyltransferase TMT1A, Methyltransferase-like protein 7A, N6-adenosine-methyltransferase TMT1A, Protein AAM-B, Thiol methyltransferase 1A, TMT1A
Target Molecular Weight (kDa)
30 kDa and 18 kDa
Sensitivity
Endogenous
Host / lsotype
Rabbit / IgG
Class
Recombinant Antibody
Clone
2P8
Expression System
CHO
Immunogen
Synthetic peptide corresponding to the C-terminal region of human METTL7A.
Purification
Protein A
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Storage Buffer
PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition
-20°C
背景
METTL7A (Methyltransferase-like 7A) is a methyltransferase enzyme that is involved in the methylation of RNA. As part of the RNA methyltransferase family, METTL7A specifically adds methyl groups to the RNA molecule, a modification that can influence various aspects of RNA metabolism, including stability, splicing, translation, and decay. While much is still being studied about the specific targets and mechanisms of METTL7A, its activity is believed to play a role in regulating gene expression and cellular processes such as cell differentiation and growth. Dysregulation of RNA methylation has been implicated in various diseases, including cancer and neurological disorders, making METTL7A an important focus of ongoing research.