Anti-eIF3h Recombinant Rabbit Monoclonal Ab
克隆号:3C16
ICC IHC WB
ERB0383
货号 规格 数量. 价格 库存
ERB0383-25μg 25μg
ERB0383-100μg 100μg
ERB0383-500μg 500μg
应用
Immunocytochemistry (ICC): 1:100
Immunohistochemistry (IHC): 1:1,000
Western Blotting (WB): 1:10,000
产品信息
Reactive Species Human, Mouse, Rat
Target UniProt ID O15372
Target Alternative Names Eukaryotic translation initiation factor 3 subunit H, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma, eIF3 p40 subunit
Target Molecular Weight (kDa) 40 kDa
Sensitivity Endogenous
Host / lsotype Rabbit / IgG
Class Recombinant Antibody
Clone 3C16
Expression System CHO
Immunogen Synthetic peptide corresponding to the C-terminal region of human eIF3h.
Purification Protein A
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein component of the eukaryotic translation initiation factor 3 (eIF3) complex, which plays a key role in the initiation of protein synthesis. eIF3h is involved in the assembly of the translation initiation complex, where it facilitates the binding of the mRNA to the ribosome and helps in the recruitment of other initiation factors. This process is crucial for the proper translation of mRNA into protein. eIF3h has been shown to interact with other subunits of eIF3 and is essential for regulating ribosome function and cellular growth. Research suggests that eIF3h may also play a role in cell cycle regulation and cellular stress responses, making it an important target in the study of cancer and other diseases related to protein synthesis and cellular growth.
参考文献
Masutani, M. et al. (2007) EMBO J 26, 3373-83.