Anti-Connexin-36 Recombinant Rabbit Monoclonal Ab
克隆号:3F23
WB
ERB0370
货号 规格 数量. 价格 库存
ERB0370-25μg 25μg
ERB0370-100μg 100μg
ERB0370-500μg 500μg
应用
Western Blotting (WB): 1:10,000
产品信息
Reactive Species Human, Rat, Mouse (predicted)
Target UniProt ID Q9UKL4
Target Alternative Names Gap junction delta-2 protein, Connexin-36 (Cx36), Gap junction alpha-9 protein, GJD2
Target Molecular Weight (kDa) 38 kDa
Sensitivity Endogenous
Host / lsotype Rabbit / IgG
Class Recombinant Antibody
Clone 3F23
Expression System CHO
Immunogen Synthetic peptide corresponding to the C-terminal region of human Connexin-36.
Purification Protein A
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
Connexin-36 (Cx36) is a protein that forms gap junctions, specialized channels that allow direct communication between adjacent cells. It is primarily expressed in the nervous system, particularly in the brain, and is crucial for electrical synapses in neurons. Connexin-36 allows the rapid transmission of electrical signals and ions between neurons, facilitating synchronized activity and communication within neural networks. This protein plays a significant role in processes such as sensory processing, motor coordination, and learning and memory. Disruptions in Cx36 function can lead to various neurological disorders, highlighting its importance in maintaining proper brain function.
参考文献
Brown, CA. et al. (2019) Cells. 8(10):1146.