Immunocytochemistry (ICC): 1:100 Immunohistochemistry (IHC): 1:100 Western Blotting (WB): 1:1,000
产品信息
Reactive Species
Human, Mouse, Rat
Target UniProt ID
Q14781
Target Alternative Names
Chromobox protein homolog 2
Target Molecular Weight (kDa)
56 kDa
Sensitivity
Endogenous
Host / lsotype
Rabbit / IgG
Class
Recombinant Antibody
Clone
4J15
Expression System
CHO
Immunogen
Synthetic peptide corresponding to the N-terminal region of human CBX2.
Purification
Protein A
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Storage Buffer
PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition
-20°C
背景
CBX2 (Chromobox 2) is a protein that belongs to the chromobox (CBX) family, which is part of the larger Polycomb group (PcG) of proteins. CBX2 plays a critical role in the regulation of gene expression through the modification of chromatin structure, often acting as a repressor of transcription. It is involved in the maintenance of cellular identity and stem cell pluripotency by regulating the silencing of specific genes during development. CBX2 has also been shown to participate in processes like cell differentiation, embryonic development, and tumorigenesis, with its expression being linked to certain cancers. Research on CBX2 continues to explore its role in gene regulation, developmental biology, and cancer progression.
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