Synthetic peptide corresponding to the extracellular domain of human MMP-14.
Purification
Protein A
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Storage Buffer
PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition
-20°C
背景
MMP-14 (Matrix Metalloproteinase-14), also known as MT1-MMP (Membrane-Type 1 Matrix Metalloproteinase), is an enzyme that plays a crucial role in the degradation of the extracellular matrix (ECM). It is a membrane-bound protease that catalyzes the breakdown of various ECM components, such as collagens and gelatin, which is important for tissue remodeling, cell migration, and wound healing. MMP-14 is involved in physiological processes like embryogenesis, neurogenesis, and inflammation. Additionally, it has been implicated in pathological conditions such as cancer metastasis and arthritis, where abnormal MMP-14 activity can contribute to tissue destruction and disease progression.
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