Immunocytochemistry (ICC): 1:100
Immunohistochemistry (IHC): 1:100
Western Blotting (WB): 1:1,000
Flow Cytometry
| Reactive Species | Human, Mouse, Rat |
|---|---|
| Target UniProt ID | P31749 |
| Target Alternative Names | RAC-alpha serine/threonine-protein kinase, Protein kinase B (PKB), Protein kinase B alpha (PKB alpha), Proto-oncogene c-Akt, RAC-PK-alpha |
| Target Molecular Weight (kDa) | 55 kDa |
| Sensitivity | Endogenous |
| Host / lsotype | Mouse / IgG1 |
| Class | Recombinant Antibody |
| Clone | SKB1-L |
| Expression System | CHO |
| Immunogen | Recombinant protein corresponding to the N-terminal region of human Akt. |
| Purification | Protein G |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300 |
| Storage Condition | -20°C |
AKT (also known as Protein Kinase B, or PKB) is a key signaling protein involved in regulating numerous cellular processes, including metabolism, growth, survival, and proliferation. It is activated by growth factors and other signaling molecules through the phosphoinositide 3-kinase (PI3K) pathway. Once activated, AKT phosphorylates a wide range of target proteins that help control cell survival, protein synthesis, glucose metabolism, and cell cycle progression. Dysregulation of AKT signaling is commonly associated with various diseases, including cancer, diabetes, and cardiovascular disorders, making it an important target for therapeutic interventions. AKT is also a critical player in the regulation of stem cell function, tissue repair, and response to stress.
仅供研究使用。不用于诊断程序。备案号：苏ICP备2025182204号-1
技术支持:库价化学
扫一扫添加
