Immunocytochemistry (ICC): 1:100
Immunohistochemistry (IHC): 1:100
Western Blotting (WB): 1:1,000
Flow Cytometry
| Reactive Species | Human |
|---|---|
| Target UniProt ID | Q9UKV8 |
| Target Alternative Names | Protein argonaute-2, Argonaute2, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2, PAZ Piwi domain protein (PPD), Protein slicer |
| Target Molecular Weight (kDa) | 70 and 95 kDa |
| Sensitivity | Endogenous |
| Host / lsotype | Mouse / IgG1 |
| Class | Recombinant Antibody |
| Clone | 2A8-L |
| Expression System | CHO |
| Immunogen | Synthetic peptide corresponding to the N-terminal region of human RARα. |
| Purification | Protein G |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300 |
| Storage Condition | -20°C |
AGO-2 (Argonaute 2) is a key protein involved in the RNA interference (RNAi) pathway, which plays a critical role in regulating gene expression at the post-transcriptional level. AGO-2 is a member of the Argonaute family of proteins and is primarily known for its role in guiding small RNA molecules, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), to complementary mRNA targets, leading to mRNA degradation or translational repression. AGO-2 is the primary effector protein in the RNA-induced silencing complex (RISC), which mediates gene silencing. Beyond RNAi, AGO-2 has also been implicated in various cellular processes, including genetic regulation, cellular development, and immune responses. Its involvement in gene regulation makes AGO-2 a key protein in both normal cellular functions and disease mechanisms, including cancer and viral infections.
仅供研究使用。不用于诊断程序。备案号：苏ICP备2025182204号-1
技术支持:库价化学
扫一扫添加
