Anti-CCL22 / MDC Recombinant Mouse Monoclonal Ab
克隆号:8D5
Sandwich ELISA
EMS0189
货号 规格 数量. 价格 库存
EMS0189-25μg 25μg
EMS0189-100μg 100μg
EMS0189-500μg 500μg
应用
Sandwich ELISA detection antibody
产品信息
Reactive Species Human
Target UniProt ID O00626
Target Alternative Names C-C motif chemokine 22, CC chemokine STCP-1, MDC(1-69), Macrophage-derived chemokine, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1
Target Molecular Weight (kDa) 8 kDa
Sensitivity Endogenous
Host / lsotype Mouse / IgG1
Class Recombinant Antibody
Clone 8D5
Expression System CHO
Immunogen Recombinant protein of full-length human CCL22.
Purification Protein G
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
CCL22 (Chemokine (C-C motif) ligand 22) is a cytokine that plays a key role in immune system regulation and inflammation. It belongs to the C-C chemokine family and primarily functions to attract T cells, particularly regulatory T cells (Tregs), to sites of immune activation and inflammation by binding to the CCR4 receptor. CCL22 is produced by various cells, including dendritic cells, macrophages, and epithelial cells, and is involved in maintaining immune tolerance, tissue repair, and the regulation of allergic reactions. Its dysregulation has been associated with autoimmune diseases, cancer, and chronic inflammatory conditions.
参考文献
Pal, R. et al. (1997) Science 278:5338.