C-C motif chemokine 1, T lymphocyte-secreted protein I-309, Small-inducible cytokine A1
Target Molecular Weight (kDa)
8.5 kDa
Sensitivity
Endogenous
Host / lsotype
Mouse / IgG1
Class
Recombinant Antibody
Clone
15D3
Expression System
CHO
Immunogen
Recombinant protein of full-length human CCL1.
Purification
Protein G
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Storage Buffer
PBS, 0.05% BSA, 0.04% Proclin 300
Storage Condition
-20°C
背景
CCL1, also known as I-309, is a chemokine involved in the recruitment of immune cells, particularly T cells and monocytes, to sites of inflammation. It is primarily produced by macrophages, fibroblasts, and endothelial cells. CCL1 plays a significant role in modulating immune responses, particularly in allergic reactions and inflammatory diseases. By attracting immune cells to areas of infection or injury, CCL1 contributes to the regulation of tissue repair and the progression of chronic inflammatory conditions. Its involvement in immune cell trafficking makes it an important factor in various immune-related diseases.