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Anti-CCL27 / CTACK Recombinant Mouse Monoclonal Ab
克隆号：6D1
Sandwich ELISA
EMS0276
货号 规格 数量. 价格 库存
EMS0276-25μg 25μg
EMS0276-100μg 100μg
EMS0276-500μg 500μg
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应用
Sandwich ELISA capture antibody
产品信息
Reactive Species Human
Target UniProt ID Q9Y4X3
Target Alternative Names C-C motif chemokine 27, Cutaneous T-cell-attracting chemokine (CTACK), CC chemokine ILC, Eskine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27
Target Molecular Weight (kDa) 10 kDa
Sensitivity Endogenous
Host / lsotype Mouse / IgG1
Class Recombinant Antibody
Clone 6D1
Expression System CHO
Immunogen Recombinant protein of full-length human CCL27.
Purification Protein G
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景
CCL27, also known as CTACK (C-C Motif Chemokine Ligand 27), is a chemokine primarily involved in the recruitment of T cells, particularly skin-homing memory T cells, to sites of inflammation. It is mainly produced by keratinocytes in the skin, as well as by other epithelial cells. CCL27 plays a key role in immune responses in the skin, contributing to the development of conditions like psoriasis, eczema, and other inflammatory skin diseases. By attracting T cells to the skin, CCL27 helps regulate immune responses and inflammation, making it an important factor in both normal skin immunity and dermatological disorders.
参考文献
Kunkel, L. and E.C. Butcher (2002) Immunity 16:1.
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