Reactive Species | Human |
---|---|
Target UniProt ID | P35243 |
Target Alternative Names | Cancer-associated retinopathy protein (Protein CAR), RCVRN |
Target Molecular Weight (kDa) | 21 kDa |
Sensitivity | Endogenous |
Host / lsotype | Rabbit / IgG |
Class | Recombinant Antibody |
Clone | 2K22 |
Expression System | CHO |
Immunogen | Recombinant protein of full length human Recoverin. |
Purification | Protein A |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.5 mg/mL |
Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300 |
Storage Condition | -20°C |
Recoverin is a calcium-binding protein primarily expressed in retinal cells, particularly in photoreceptors. It plays a key role in the regulation of visual signal transduction by modulating the activity of rhodopsin kinase, an enzyme involved in the phototransduction pathway. Recoverin acts as a calcium sensor, influencing the ability of photoreceptor cells to respond to light stimuli, thus contributing to visual adaptation and the ability to process light signals efficiently. Its function is crucial for maintaining the sensitivity of the retina, and defects in recoverin have been linked to certain retinal disorders.