Reactive Species | Human, Monkey, Rat (predicted) |
---|---|
Target UniProt ID | P31946 |
Target Alternative Names | Protein 1054 Protein kinase C inhibitor protein 1 (KCIP-1) |
Target Molecular Weight (kDa) | 28 kDa |
Sensitivity | Endogenous |
Host / lsotype | Rabbit / IgG |
Class | Recombinant Antibody |
Clone | 1G5 |
Expression System | CHO |
Immunogen | Synthetic peptide corresponding to the C-terminal region of human 14-3-3 β/α. |
Purification | Protein A |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.5 mg/mL |
Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300 |
Storage Condition | -20°C |
14-3-3 β/α is a member of the 14-3-3 protein family, which consists of highly conserved regulatory proteins involved in a variety of cellular processes. 14-3-3 β/α (also known as 14-3-3β or 14-3-3α) functions primarily as a molecular scaffold that interacts with and regulates numerous target proteins by binding to phosphoserine or phosphothreonine motifs. This interaction affects critical cellular functions such as signal transduction, cell cycle regulation, apoptosis, and stress response. 14-3-3 β/α is involved in modulating the activity of key signaling pathways, including those related to protein kinases and phosphatases. Dysregulation of 14-3-3 β/α has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases, making it an important target for ongoing research in cell signaling and therapeutic development.