| Reactive Species | Human, Mouse |
|---|---|
| Target UniProt ID | Q96HS1 |
| Target Alternative Names | Serine/threonine-protein phosphatase PGAM5 (mitochondrial), Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5 |
| Target Molecular Weight (kDa) | 32 kDa |
| Sensitivity | Endogenous |
| Host / lsotype | Rabbit / IgG |
| Class | Recombinant Antibody |
| Clone | 3K3 |
| Expression System | CHO |
| Immunogen | Recombinant protein corresponding to the N-terminal region of human PGAM5. |
| Purification | Protein A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300 |
| Storage Condition | -20°C |
PGAM5 (Phosphoglycerate Mutase Family Member 5) is a mitochondrial protein that plays a key role in regulating cellular stress responses and mitochondrial function. It belongs to the phosphoglycerate mutase (PGAM) family, although its specific enzymatic activity differs from traditional PGAMs. PGAM5 is involved in the maintenance of mitochondrial dynamics, particularly by modulating the mitochondrial fusion and fission processes, and regulating cell death pathways. It is known to interact with several key proteins involved in mitochondrial quality control, including those involved in apoptosis and mitophagy. Research on PGAM5 focuses on its role in cell survival, stress response, and its potential implications in diseases related to mitochondrial dysfunction, such as neurodegenerative diseases and cancer.
仅供研究使用。不用于诊断程序。备案号：苏ICP备2025182204号-1
技术支持:库价化学
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