Anti-ACAD10 Recombinant Rabbit Monoclonal Ab
克隆号:2K2
IHC WB
ERB0249
货号 规格 数量. 价格 库存
ERB0249-25μg 25μg
ERB0249-100μg 100μg
ERB0249-500μg 500μg
应用

Immunohistochemistry (IHC): 1:100
Western Blotting (WB): 1:10,000

产品信息
Reactive Species Human, Rat
Target UniProt ID Q6JQN1
Target Alternative Names Acyl-CoA dehydrogenase family member 10
Target Molecular Weight (kDa) 130 kDa
Sensitivity Endogenous
Host / lsotype Rabbit / IgG
Class Recombinant Antibody
Clone 2K2
Expression System CHO
Immunogen Synthetic peptide corresponding to the C-terminal region of human ACAD10.
Purification Protein A
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.04% Proclin 300
Storage Condition -20°C
背景

ACAD10 (Acyl-CoA dehydrogenase family member 10) is an enzyme involved in the metabolism of fatty acids, particularly in the process of mitochondrial fatty acid oxidation. It is part of the acyl-CoA dehydrogenase family, which plays a key role in breaking down fatty acids to produce energy for cells. ACAD10 specifically catalyzes the initial step in the degradation of medium-chain fatty acids, contributing to cellular energy production, particularly during periods of fasting or increased energy demand. Mutations in the ACAD10 gene have been linked to metabolic disorders, such as mitochondrial diseases and impaired fatty acid oxidation, which can lead to a variety of symptoms, including muscle weakness, hypoglycemia, and cardiomyopathy. Research into ACAD10 aims to better understand its role in metabolism and its potential as a therapeutic target for related metabolic disorders.

参考文献

Bloom, K. et al.(2020) PLoS One. 15(12):e0242445.